The Science of Cancer Treatment

In the first part of this book, we have asked practising clinicians in different specialities to assess the contributions of biology and of empiricism to current approaches to treatment.

Author: B.A. Ponder

Publisher: Springer

ISBN: UOM:39015017959571

Category: Gardening

Page: 211

View: 765

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Many of the most effective treatments for disease have been discovered empir ically. Nowadays, however, we think that understanding the biology of a disease will lead us to design better treatments, and to improve the application of treatments we already have. To accomplish this, vast sums are expended on cancer research. Even so, to the casual observer of clinical oncology the proliferation of studies and trials of ever-different combinations of therapies looks like empiricism, at the best. In the first part of this book, we have asked practising clinicians in different specialities to assess the contributions of biology and of empiricism to current approaches to treatment. In the second part, we have asked researchers in different areas of biology applied to cancer to assess the present and likely future impact of their type of biology on cancer treatment and control. IX 1 Surgery M.BAUM OBJECTIVES OF CANCER TREATMENT The objectives of cancer treatment can be defined according to population requirements or according to the needs of the individual. As far as the population is concerned, Government authorities are entitled to expect that cancer treatment will lead to mortality reductions and cost containment.

The Science of Cancer Treatment

LESSONS FROM LEUKAEMIA, LYMPHOMA AND CHILDHOOD CANCERS Recognition of the fact and possible causes of failure of cancer chemotherapy has also played a part in the development of current approaches to the treatment of cancer, ...

Author: B.A. Ponder

Publisher: Springer Science & Business Media

ISBN: 9789400907096

Category: Medical

Page: 224

View: 878

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Many of the most effective treatments for disease have been discovered empir ically. Nowadays, however, we think that understanding the biology of a disease will lead us to design better treatments, and to improve the application of treatments we already have. To accomplish this, vast sums are expended on cancer research. Even so, to the casual observer of clinical oncology the proliferation of studies and trials of ever-different combinations of therapies looks like empiricism, at the best. In the first part of this book, we have asked practising clinicians in different specialities to assess the contributions of biology and of empiricism to current approaches to treatment. In the second part, we have asked researchers in different areas of biology applied to cancer to assess the present and likely future impact of their type of biology on cancer treatment and control. IX 1 Surgery M.BAUM OBJECTIVES OF CANCER TREATMENT The objectives of cancer treatment can be defined according to population requirements or according to the needs of the individual. As far as the population is concerned, Government authorities are entitled to expect that cancer treatment will lead to mortality reductions and cost containment.

Cancer Improving Your Odds

You should read this book with a highlighter and pencil at your side. This book has been extensively researched, and some of the information found here you will probably find in no other book or medical website.

Author: John Herron

Publisher:

ISBN: 1709219939

Category:

Page: 547

View: 484

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Are you looking for actionable steps that you can take to assist your cancer treatment, or possibly prevent cancer in the first place? Steps with scientific evidence that they are effective? Something that you won't be embarrassed to discuss with your family doctor or oncologist? Something that can improve your immune system and general health? That is exactly what you will find in this book. Read on for... Actionable methods for naturally treating and preventing cancer (the scientific way, not the internet blogger way) Simple steps that you can add to your medical treatment to Improve Your Odds of successfully fighting cancer 100% backed by science that you, or your doctor, can easily verify Easy to read and understand, but formatted so that you can share the science with your doctor Improve your immune system and general health Evidence that some of the recommendations may significantly improve immunotherapy outcomes, as well as benefit chemotherapy and radiotherapy treatments. New research information that has the potential to save many lives My hope is you'll use this information to improve your medical treatment, not replace it. Even though some of the natural treatments have been scientifically shown to be very effective on their own, they are even more effective when used in conjunction with modern medicine. This is called "adjuvant" therapy. You should strive to "Improve Your Odds" of beating cancer, not thumb your nose at modern medicine. You do not need a scientific or medical background to understand this narrative--but its claims are evidenced with scientific abstracts that your doctor will appreciate (abstracts that you can skip if you wish to cut your reading time in half!). You will find that all recommendations have solid evidence behind them; this isn't just another book where someone is simply making it all up and telling you what you want to hear. You should read this book with a highlighter and pencil at your side. This book has been extensively researched, and some of the information found here you will probably find in no other book or medical website. There is a special emphasis on how you can improve your immune system to better fight almost any cancer, even before you know you have it. You aren't trying to fire your doctor; you just want to help "Improve Your Odds." This book will help you do that. Your oncologist will want to know all of the supplements you are taking and why. This book includes the scientific abstracts and the information they need to find the full research studies. This will explain the "why" so you don't have to. They may also want to geek out on all of this science as they rarely get exposed to research on natural cancer treatments. Finally, this book enables you to take some control over your cancer treatment or genetic predisposition. In fact, most of the recommendations in this book are great even if you are healthy, as they can help prevent cancer and improve your immune system, too. Whether you may have breast cancer, skin cancer, lung cancer, etc., improving the immune system and your body's ability to fight cancer is always beneficial.

Advancing the Science of Cancer in Latinos

Research suggests that a myriad of factors, operating at multiple levels of influence, negatively influence cervical cancer screening and receipt of follow-up treatment in a timely fashion. Factors at the individual level include low ...

Author: Amelie G. Ramirez

Publisher: Springer Nature

ISBN: 9783030292867

Category: Medical

Page: 329

View: 855

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This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress. The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium; the chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos. Topics included among the chapters: Colorectal cancer disparities in Latinos: Genes vs. EnvironmentBreast cancer risk and mortality in women of Latin American originDifferential cancer risk in Latinos: The role of dietOvercoming barriers for Latinos on cancer clinical trialsEs tiempo: Engaging Latinas in cervical cancer researchEmerging policies in U.S. health care Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.

In the Darker Shadow of Science

Incredible as it may seem, it is still not generally recognised that this is the main mechanism whereby cancerous cells are selectively destroyed in the living body. - 2 - A few years after the project began isolated reports in the medical ...

Author: N. Jones Robert N. Jones

Publisher: iUniverse

ISBN: 1440173745

Category: Biography & Autobiography

Page: 560

View: 721

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SYNOPSIS A few decades ago mention of cancer emerged from hushed embarrassed silence into the brightness of the public arena. Previously the affliction had been referred to as little as possible; its victims were described as having died `after a long illness'. Once the disease was out of the shadows fear, hopelessness, pain, tragedy, bereavement and enforced loneliness came to be openly spoken and written about. The gigantic costs of modern treatments, sometimes causing homes to be mortgaged in the illusory hope of saving loved ones, bring commerce, politics and financial blackmail into noisy public collision. In the world of books what began as a slender trickle of cancer experiences and biographies has become a flood. A similar phenomenon attends Alzheimer's disease today. Always victims and relatives occupy centre stage; doctors and scientists sensibly remain silent. One reason may be the poor record of success. One in three of the UK population will at some time be diagnosed with the disease; only a twelfth will survive. In cancer treatment there has not been a great deal to celebrate. The present autobiography grabs the vacant ground, and covers almost half the life of a scientist dedicated to finding a solution to the most difficult problem faced by medicine ancient and modern. Let the reader not be put off by the word science in the title. In the experience of the author the dichotomy between science and the arts, eloquently described by CP Snow in his famous lecture The Two Cultures and the Scientific Revolution, has taken on the form of resentment towards science. In a modern society, where so much of the ease of our existence is due to the advances made by science and technology, everybody has a social duty to keep him/herself informed. The benefits of science are everywhere around us. Cars, aeroplanes, Tvs, computers, medicine; the list is endless. Nobody can afford to ignore its myriad manifestations, and that includes stories of discovery and politics. Some individuals parade their ignorance of science as a badge of honour; their idle and insidious attitudes are dangerous for us all. But all is not well. Anyone who believes that the conduct of research and administration in cancer is guided by decency, morality and integrity is in for a violent shock. The world of science is presented in the raw. Nothing is spared, not even the author himself. Intrigue, ruthless double-dealing, commercial pressures, jealousy, deceit, sabotage, corruption and betrayal, especially the irreversible professional damage caused by drug-induced psychosis in a senior colleague, enliven the narrative. The scientific content has been simplified with a predominantly lay readership in mind; for easy avoidance the more technical passages, comprising 3% of the text, are rendered in italics. A glossary and an index are appended. The peculiar arrival in 1974 of a radical idea led to a discovery which opened up an entirely new perspective on cancer treatment. Seriously disadvantaged by already being in his early forties at the commencement of the project, about to be out of a job, and lacking a medical qualification, the author was beguiled into making the naive and foolish error that, once established, a concept which humanely revolutionised the field of cancer therapy could not but find acceptance. The idea was simple, original and elegant; namely, that disrupting energy metabolism within cancer cells might perhaps be the key to controlling the growth of malignant tumours. In fact the concept turned out to be a revolutionary discovery. Incredible as it may seem, it is still not generally recognised that this is the main mechanism whereby cancerous cells are selectively destroyed in the living body. - 2 - A few years after the project began isolated reports in the medical literature of cancer regression in patients treated with relatively innocuous well-known drugs long out of patent we

The Death of Cancer

With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

Author: Vincent T. DeVita, Jr., M.D.

Publisher: Sarah Crichton Books

ISBN: 9780374714178

Category: Medical

Page: 336

View: 810

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Cancer touches everybody’s life in one way or another. But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible. Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers. With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

A Beginner s Guide to Targeted Cancer Treatments

With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge.

Author: Elaine Vickers

Publisher: John Wiley & Sons

ISBN: 9781119126829

Category: Medical

Page: 360

View: 472

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The accessible guide to the principles behind new, more targeted drug treatments for cancer Written for anyone who encounters cancer patients, cancer data or cancer terminology, but have no more than a passing knowledge of cell biology. A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over 100 original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Dr Vickers translates a complex and often overwhelming topic into something digestible and easily understood. She also explains what cancer is, how it behaves and how our understanding of cancer has changed in recent years. Each chapter takes the reader through how new cancer drugs work and their benefits and limitations. With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge. This vital resource: Offers the latest insights into cancer biology Provides a broad understanding of how targeted cancer treatments work Describes many of the new immunotherapy approaches to cancer treatment, such as checkpoint inhibitors and CAR-modified T cells Helps readers feel confident discussing treatment options with colleagues and patients Provides an overview of which treatments are relevant to each of the most common solid tumours and haematological cancers, and the rationale behind them Demystifies the jargon – terms such as the EMT, cancer stem cells, monoclonal antibodies, kinase inhibitors, angiogenesis inhibitors etc. Explains the resistance mechanisms to many new treatments, including issues such as the way cancer cells diversify and evolve and the complex environment in which they live

After Cancer Care

After Cancer Care is the much-needed authoritative, approachable guide that fills this gap.

Author: Gerald Lemole, MD

Publisher: Rodale

ISBN: 9781623365028

Category: Health & Fitness

Page: 306

View: 927

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After the intense experience and range of emotion that comes with surgery, radiation, or chemotherapy (or all three), cancer patients often find themselves with little or no guidance when it comes to their health post-treatment. After Cancer Care is the much-needed authoritative, approachable guide that fills this gap. It includes information on how to maintain physical health--with chapters on epigenetics, nutrition, and exercise--as well as emotional health through stress management techniques. The cutting-edge and growingly popular science of Epigenetics has shown that you are not stuck with your genetic history: your choices in diet, exercise, and even relationships can help determine whether or not your genes promote cancer, and therefore determine your propensity for relapse. Your lifestyle has an effect on the most common types of cancer including breast cancer, prostate cancer, melanoma, endometrial cancer, colon cancer, bladder cancer, and lymphoma. The doctors present easy-to-incorporate lifestyle changes to help you “turn on” hundreds of genes that fight cancer, and “turn off” the ones that encourage cancer, while recommending lifestyle plans to address each type. In addition, they share 34 healthy recipes and tips on staying active and exercising, detoxifying your house and environment, and taking supplements to help prevent relapse. With more than three decades of post-cancer-care experience, Drs. Lemole, Mehta, and McKee break down the science into palatable, practical takeaways so that you can drastically improve your quality of life and enjoy many years of cancer-free serenity.

The Basic Science of Oncology

This edition is substantially revised to reflect the major scientific advances, especially with respect to molecular genetics.

Author: Ian Tannock

Publisher: McGraw-Hill

ISBN: UOM:39015042163280

Category: Medical

Page: 564

View: 915

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Reviews the fast-moving and critically important topics in cancer causation, cancer biology, and the biology underlying cancer treatment. This edition is substantially revised to reflect the major scientific advances, especially with respect to molecular genetics. Additional coverage includes state-of-the-art updates on cancer therapy including new drugs and experimental radiotherapy. Interesting, relevant, and not overpowering in length, the book appeals to a wide audience including physicians, nurses, and medical students as well as radiation therapists.