Conclusions CLL is the most common leukemia in adults in the developed world.
... Moreover, some drivers could be targeted pharmacologically, even when
present at subclonal level, thus avoiding clonal selection and disease
refractoriness. ... Further Reading Falchi, L., Keating, M.J., Marom, E.M., Truong,
M.T., Schlette, E.J., Sargent, R.L., Trinh, L., Wang, X., ... Nadeu, F., Delgado, J.,
Royo, C., Baumann, T., Stankovic, T., 416 Chronic Lymphocytic Leukemia:
Pathology and Genetics.
Publisher: Academic Press
Encyclopedia of Cancer, Third Edition provides a comprehensive, up-to-date overview of the multiple facets of the disease, including research, treatment and societal impact. This new edition comprises 180 contributions from renown experts who present the latest in Mechanisms, Hallmarks of Cancer, Causes of Cancer, Prevention and Control, Diagnosis and Therapy, Pathology and the Genetics of specific Cancers. Readers will find a comprehensive overview of the main areas of oncology, including etiology, mechanisms, prevention, and treatments, from basic science to clinical applications and public health, all set alongside the latest advances and hot topics that have emerged since the previous edition. Topics of interest in the field, including genomics and epigenomics, our understanding of the causes of cancer and the approaches to preventing it (e.g., HPV vaccination, role of obesity and nutrition, molecular markers of environmental exposures), new screening techniques (e.g., low-dose CT for lung cancer) and improvements in the treatment of many cancers (e.g., breast cancer, lung adenocarcinoma) are comprehensively and authoritatively presented. Comprises 180 contributions from renowned experts who present the latest in mechanisms, hallmarks of cancer, causes, prevention and control, diagnosis and therapy, pathology and genetics Presents a comprehensive overview of the main areas of oncology, including etiology, mechanisms, prevention, and treatments, from basic science to clinical applications and public health