Risk Assessment Methods

Approaches for Assessing Health and Environmental Risks V.T. Covello, M.W. Merkhoher ... However , nearly all such books focus narrowly on specific subsets of available risk assessment methods : namely , those methods that have been ...

Author: V.T. Covello

Publisher: Springer Science & Business Media

ISBN: 0306443821

Category: Medical

Page: 319

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This volume fills the need for a comprehensive guidebook and reference for risk assessment techniques. Within a generalized conceptual framework the authors clarify and integrate basic concepts; critique current methodologies; and teach the selection and application of a specific method and the interpretation of its results. The work makes these seemingly bewildering techniques accessible to readers from all disciplines.

Benefit Risk Assessment Methods in Medical Product Development

The temporal course of risk was assessed by assessing the cumulative excess number of events over time between vorapaxar and placebo groups ... 11.4 Discussion This chapter summarizes a multifaceted approach to the assessment of balance ...

Author: Qi Jiang

Publisher: CRC Press

ISBN: 9781482259377

Category: Mathematics

Page: 296

View: 660

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Guides You on the Development and Implementation of B–R Evaluations Benefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present practical examples, lessons learned, and best practices that illustrate how to conduct structured B–R assessment in clinical development and regulatory submission. The first section of the book discusses the role of B–R assessments in medicine development and regulation, the need for both a common B–R framework and patient input into B–R decisions, and future directions. The second section focuses on legislative and regulatory policy initiatives as well as decisions made at the U.S. FDA’s Center for Devices and Radiological Health. The third section examines key elements of B–R evaluations in a product’s life cycle, such as uncertainty evaluation and quantification, quantifying patient B–R trade-off preferences, ways to identify subgroups with the best B–R profiles, and data sources used to assist B–R assessment. The fourth section equips practitioners with tools to conduct B–R evaluations, including assessment methodologies, a quantitative joint modeling and joint evaluation framework, and several visualization tools. The final section presents a rich collection of case studies. With top specialists sharing their in-depth knowledge, thought-provoking considerations, and practical advice, this book offers comprehensive coverage of B–R evaluation methods, tools, and case studies. It gives practitioners a much-needed toolkit to develop and conduct their own B–R evaluations.

Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment

The present volume aims to present new concepts and methods for cancer and human health risk assessment which account for the wealth of new biological data and biological and medical concepts . This comprises mathematical , statistical ...

Author: Lutz Edler

Publisher: John Wiley & Sons

ISBN: 0470857560

Category: Mathematics

Page: 512

View: 588

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Human health risk assessment involves the measuring of risk of exposure to disease, with a view to improving disease prevention. Mathematical, biological, statistical, and computational methods play a key role in exposure assessment, hazard assessment and identification, and dose-response modelling. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment is a comprehensive text that accounts for the wealth of new biological data as well as new biological, toxicological, and medical approaches adopted in risk assessment. It provides an authoritative compendium of state-of-the-art methods proposed and used, featuring contributions from eminent authors with varied experience from academia, government, and industry. Provides a comprehensive summary of currently available quantitative methods for risk assessment of both cancer and non-cancer problems. Describes the applications and the limitations of current mathematical modelling and statistical analysis methods (classical and Bayesian). Includes an extensive introduction and discussion to each chapter. Features detailed studies of risk assessments using biologically-based modelling approaches. Discusses the varying computational aspects of the methods proposed. Provides a global perspective on human health risk assessment by featuring case studies from a wide range of countries. Features an extensive bibliography with links to relevant background information within each chapter. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment will appeal to researchers and practitioners in public health & epidemiology, and postgraduate students alike. It will also be of interest to professionals working in risk assessment agencies.

Risk Assessment Methods

There are already many books on risk assessment-the trouble is that they all seem to be about different sUbjects! This book takes another approach.

Author: V.T. Covello

Publisher: Springer Science & Business Media

ISBN: 9781489912169

Category: Technology & Engineering

Page: 318

View: 416

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Much has already been written about risk assessment. Epidemiologists write books on how risk assessment is used to explore the factors that influence the distribution of disease in populations of people. Toxicologists write books on how risk assess ment involves exposing animals to risk agents and concluding from the results what risks people might experience if similarly exposed. Engineers write books on how risk assessment is utilized to estimate the risks of constructing a new facility such as a nuclear power plant. Statisticians write books on how risk assessment may be used to analyze mortality or accident data to determine risks. There are already many books on risk assessment-the trouble is that they all seem to be about different sUbjects! This book takes another approach. It brings together all the methods for assessing risk into a common framework, thus demonstrating how the various methods relate to one another. This produces four important benefits: • First, it provides a comprehensive reference for risk assessment. This one source offers readers concise explanations of the many methods currently available for describing and quantifying diverse types of risks. • Second, it consistently evaluates and compares available risk assessment methods and identifies their specific strengths and limitations. Understand ing the limitations of risk assessment methods is important. The field is still in its infancy, and the problems with available methods are disappoint ingly numerous. At the same time, risk assessment is being used.

Risk Assessment Principles for the Industrial Hygienist

In this appendix, the different risk assessment methodologies of the U.S. Occupational Safety and Health Administration (OSHA) and the U.S. Environmental Protection Agency (EPA) are compared. A case study using the example of primary ...

Author: M. A. Jayjock

Publisher: AIHA

ISBN: 9780932627971

Category: Medical

Page: 110

View: 553

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This relevant and scholarly text masterfully integrates health risk assessment information and its importance to IH and environmental scientists. Topics include science and judgment, risk assessment, risk management, and the future of industrial hygiene.

Animal Damage Control Program Appendix P Risk assessment of wildlife damage control methods used by the USDA Animal Damage Control Program Appendix Q USEPA approved registrations for pesticides used in the APHIS Animal Damage Control Program

Qualitative risk assessments of resource management and physical exclusion methods were conducted . This decision to use qualitative assessment reflects the state of risk assessment approaches and the availability of data .

Author: Animal Damage Control Program (U.S.)

Publisher:

ISBN: CORNELL:31924073132627

Category: Pests

Page:

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Public Health Risk Assessment for Human Exposure to Chemicals

Chapter 3 PRINCIPLES AND CONCEPTS IN RISK ASSESSMENT In its application to chemical exposure problems , the risk assessment process is used ... In general , risk assessment methods commonly encountered in the literature of environmental ...

Author: K. Asante-Duah

Publisher: Springer Science & Business Media

ISBN: 1402009208

Category: Medical

Page: 352

View: 251

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In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.

The Security Risk Assessment Handbook

Security risk assessments done without solid methods and accurate data collection (e.g., surveys, internal self-reviews, and checklists) can lead to costly mistakes and inaccurate strategic directions. The security risk assessment is ...

Author: Douglas Landoll

Publisher: CRC Press

ISBN: 9781000413205

Category: Business & Economics

Page: 512

View: 668

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Conducted properly, information security risk assessments provide managers with the feedback needed to manage risk through the understanding of threats to corporate assets, determination of current control vulnerabilities, and appropriate safeguards selection. Performed incorrectly, they can provide the false sense of security that allows potential threats to develop into disastrous losses of proprietary information, capital, and corporate value. Picking up where its bestselling predecessors left off, The Security Risk Assessment Handbook: A Complete Guide for Performing Security Risk Assessments, Third Edition gives you detailed instruction on how to conduct a security risk assessment effectively and efficiently, supplying wide-ranging coverage that includes security risk analysis, mitigation, and risk assessment reporting. The third edition has expanded coverage of essential topics, such as threat analysis, data gathering, risk analysis, and risk assessment methods, and added coverage of new topics essential for current assessment projects (e.g., cloud security, supply chain management, and security risk assessment methods). This handbook walks you through the process of conducting an effective security assessment, and it provides the tools, methods, and up-to-date understanding you need to select the security measures best suited to your organization. Trusted to assess security for small companies, leading organizations, and government agencies, including the CIA, NSA, and NATO, Douglas J. Landoll unveils the little-known tips, tricks, and techniques used by savvy security professionals in the field. It includes features on how to Better negotiate the scope and rigor of security assessments Effectively interface with security assessment teams Gain an improved understanding of final report recommendations Deliver insightful comments on draft reports This edition includes detailed guidance on gathering data and analyzes over 200 administrative, technical, and physical controls using the RIIOT data gathering method; introduces the RIIOT FRAME (risk assessment method), including hundreds of tables, over 70 new diagrams and figures, and over 80 exercises; and provides a detailed analysis of many of the popular security risk assessment methods in use today. The companion website (infosecurityrisk.com) provides downloads for checklists, spreadsheets, figures, and tools.

Risk Assessment

Guides the reader through a risk assessment and shows them the proper tools to be used at the various steps in the process This brand new edition of one of the most authoritative books on risk assessment adds ten new chapters to its pages ...

Author: Lee T. Ostrom

Publisher: John Wiley & Sons

ISBN: 9781119483465

Category: Technology & Engineering

Page: 552

View: 943

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Since the first edition of the book was published there have been several changes in the types of risk individuals, businesses, and governments are being exposed to. Cyber-attacks are more frequent and costly and lone-wolf style terrorist attacks are more common; events not addressed in the first edition. The book continues to provide a resource that leads the reader through a risk assessment and shows them the proper tools to be used at the various steps in the process. This book also provides students studying safety and risk assessment a resource that assists them in understanding the various risk assessment tools and presents readers with a toolbox of techniques that can be used to aid them in analyzing conceptual designs, completed designs, procedures and operational risk. On top of the ten new chapters the new edition also includes expanded case studies and real-life examples; coverage on risk assessment software like SAPPHIRE and RAVEN; and end-of-chapter questions for students with a solutions manual for academic adopters. The approach to the book remains the same and is analogous to a toolkit. The user locates the tool that best fits the risk assessment task they are performing. The chapters of the book progress from the concept of risk, through the simple risk assessment techniques, and into the more complex techniques. In addition to discussing the techniques, this book presents them in a form that the readers can readily adapt to their particular situation. Each chapter, where applicable, presents the technique discussed in that chapter and demonstrates how it is used.

Toxicological Risk Assessment for Beginners

which chemical and nonchemical stressors should be included in component-based risk assessments; the extent to which the assumptions inherent in component-based risk assessment methodologies have been examined experimentally; methods to ...

Author: José A. Torres

Publisher: Springer

ISBN: 9783319127514

Category: Medical

Page: 250

View: 459

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This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypothetical case studies. Toxicological Risk Assessment for Beginners aims not to create an expert, but rather to provide readers with their first understanding of the risk assessment topic. This book was designed with the student in mind. We simplify a complex process for beginners and balance theory with practical aspects, but remain fluid enough to increase difficulty with case studies. By incorporating an action based, step by step approach to learning the risk assessment process, this book provides its readers with an elementary understanding of how the risk assessment process is initiated, developed and finished, making it a valuable guide for graduate students, post-doctoral fellows and early career scientists in industry.