Research in Psychiatry

Concern with serious shortages of research personnel in psychiatry dates back to the mid-1940s. Eight years after the establishment of the National Institute of Mental Health (NIMH) in 1946, the Career Investigator Grant Program was ...

Author: L.K. George Hsu

Publisher: Springer Science & Business Media

ISBN: 9781489906885

Category: Medical

Page: 482

View: 304


This multiauthored textbook is directed to the psychiatric resident and other professionals who are interested in the issues, strategies, and methods of psychiatric research. Although the field of psychiatry has not attained the scientific rigor and clinical sophistication of some of its sister disciplines in the medical arena, considerable progress has been made in the last decade or two, and a full understanding of the types of articles that now appear in such publications as the American Journal of Psychiatry, the Archives of General Psychi atry, and the Journal of the American Academy of Child and Adolescent Psychiatry requires a fair amount of knowledge about research design and strategy. Whereas articles in psychiatric journals 20 years ago dealt mainly with psycho dynamic topics and utilized nonexperimental observations, today their counter parts are concerned mostly with psychobiology, clinical features, diagnosis, and treatment, and employ scientific experimental designs. The trend of applying scientific methodology to research in psychiatry is increasing and undoubtedly will continue to do so in the future.

Research Training in Psychiatry Residency

Strategies for Reform Institute of Medicine, Board on Neuroscience and Behavioral Health, Committee on Incorporating Research into Psychiatry Residency Training Thomas F. Boat, Kathleen M. Patchan, Michael T. Abrams.

Author: Institute of Medicine

Publisher: National Academies Press

ISBN: 9780309090711

Category: Medical

Page: 270

View: 136


The number of psychiatric researchers does not seem to be keeping pace with the needs and opportunities that exist in brain and behavioral medicine. An Institute of Medicine committee conducted a broad review of the state of patient-oriented research training in the context of the psychiatry residency and considered the obstacles to such training and strategies for overcoming those obstacles. Careful consideration was given to the demands of clinical training. The committee concluded that barriers to research training span three categories: regulatory, institutional, and personal factors. Recommendations to address these issues are presented in the committee’s report, including calling for research literacy requirements and research training curricula tailored to psychiatry residency programs of various sizes. The roles of senior investigators and departmental leadership are emphasized in the report, as is the importance of longitudinal training (e.g., from medical school through residency and fellowship). As there appears to be great interest among numerous stakeholders and a need for better tracking data, an overarching recommendation calls for the establishment of a national body to coordinate and evaluate the progress of research training in psychiatry.

Research in Mental Health Computer Applications

J.W .; and Getto , C. The computer psychiatrist : How Hedlund , J.L .; Vieweg , B.W .; and Cho , D.W. Mental far have we come ? Where are we heading ? How far health computing in the 1980s . II . Clinical dare we go ? Behavior Research ...



ISBN: UOM:39015029116921

Category: Community health aides

Page: 127

View: 282


Recent Advances in Psychiatry from Psycho Neuro Immunology Research Autoimmunencephalitis Autoimmune Encephalopathy Mild Encephalitis

Sabine Müller* and Rita Riedmüller Mind and Brain Research, Psychiatry and Psychotherapy, CCM, Charité - Universitätsmedizin Berlin, Berlin, Germany Keywords: schizophrenia, ethics, mild encephalitis, stigmatization, discrimination ...

Author: Karl Bechter

Publisher: Frontiers Media SA

ISBN: 9782889459506



View: 174


Growing evidence derived from cerebrospinal fluid (CSF), neuropathological, imaging, genetic, and epidemiological studies link neuroinflammation and immune dysregulation to a subset of individuals with a variety of severe mental disorders (SMDs), including affective and non-affective psychotic disorders. Further, the recent discoveries of neuronal surface antibodies (NSAs) in autoimmune encephalitis (AE) presenting with diverse neuropsychiatric disorders such as psychosis and cognitive decline, among many others, provides further support to the notion that CNS autoimmunity and neuroinflammation can contribute to the neurobiology of psychiatric disturbances. Further, these immune mechanisms may contribute to a subset of patients currently diagnosed as having treatment-resistant SMDs such as schizophrenia and major depressive disorder. Additionally, mounting data indicate that various infections can serve as an immunological trigger of aberrant immune responses, presumably by causing release of excess neural antigen, thereby giving rise to NSAs or aberrant immune cellular responses to give rise to primary or secondary psychiatric disorders such as schizophrenia and those associated with AE, respectively. Collectively, these findings support the “mild encephalitis” hypothesis of SMD. The significant overlap among AE-associated psychosis, systemic autoimmune disorder-associated psychosis, and psychotic disorders associated with pathological processes involving inflammation and immune dysregulation has also prompted some authors to adopt the term “autoimmune psychosis” (AP). This term reflects that this psychosis subtype is mechanistically linked to complex neuroimmune and inflammatory signalling abnormalities that can be responsive to early immunomodulatory treatment. It also suggests that a subset of AP might represent an incomplete or “forme fruste” subtype of AE presenting with dominant or pure psychiatric symptoms mimicking primary psychiatric illnesses. Because data indicate that delayed diagnosis and treatment may lead to permanent sequelae, early recognition of AP utilizing neurodiagnostic workup (e.g., CSF analysis, neuroimaging, and EEG) and its early treatment with appropriate immunotherapy are paramount to a meaningful recovery. This eBook will provide an overview of the current knowledge and research areas from epidemiology, risk factors and diagnosis to the management of these conditions, in this rapidly emerging field, helping to bridge the gaps in knowledge that currently exist in the disciplines of Psychiatry, Neurology, and Neuroimmunology.

Elements of Clinical Research in Psychiatry

This volume covers everything from starting a career to measurement and assessment methods, and from statistics to the use of human subjects, as well as related ethics and misconduct issues.

Author: James Edward Mitchell

Publisher: American Psychiatric Pub

ISBN: UOM:39015042484314

Category: Medical

Page: 232

View: 655


This volume covers everything from starting a career to measurement and assessment methods, and from statistics to the use of human subjects, as well as related ethics and misconduct issues. Also included is research support -- provides a roadmap for those seeking research support in the U.S., detailing how to write grants from the ground up.