Rabbit Biotechnology

Rabbit genomics, transgenesis, cloning and models Louis-Marie Houdebine, Jianglin Fan. 2.5 Storage of Rabbit Semen For temporally storage, if spermatozoa is kept in appropriate buffer and temperature, we can maintain it for several ...

Author: Louis-Marie Houdebine

Publisher: Springer Science & Business Media

ISBN: 9789048122271

Category: Medical

Page: 136

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Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.

Rabbit Biotechnology

Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.

Author: Louis-Marie Houdebine

Publisher: Springer

ISBN: 9048122805

Category: Medical

Page: 136

View: 370

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Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.

Biotechnology for Sustainable Agriculture

Rabbit Biotechnology. Rabbit genomics, transgenesis, cloning and models. Springer (Publisher), http://www.springer.com/biomed/book/97890-481-2226-4. Houdebine, L. M., Dinnye ́s, A., Banati, D., Kleiner, J., & Carlander, D. (2008).

Author: Ram Lakhan Singh

Publisher: Woodhead Publishing

ISBN: 9780128122389

Category: Technology & Engineering

Page: 446

View: 985

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Biotechnology for Sustainable Agriculture: Emerging Approaches and Strategies is an outstanding collection of current research that integrates basic and advanced concepts of agricultural biotechnology with future development prospects. Using biotechnology with sustainable agriculture effectively contributes to gains in agricultural productivity, enhanced food security, reduced poverty and malnutrition, and more ecologically sustainable means of food production. Written by a panel of experts, this book is unique in its coverage of the broad area of biotechnology for sustainable agriculture. It includes intriguing topics and discussions of areas such as recombinant DNA technology and genetic engineering. Identifies and explores biotechnological tools to enhance sustainability Encompasses plant and microbial biotechnology, nanotechnology and genetic engineering Focuses on plant biotechnology and crop improvement to increase yield and resilience Summarizes the impact of climate change on agriculture, fisheries and livestock

Rabbit

30 KazutoshiNishijima,'Basic Methods for Experimental Rabbits', in Rabbit Biotechnology: RabbitGenomics, Transgenesis, Cloning, and Models,ed.L.M. HoudebineandJ.Fan (Berlin, 2009), pp. 13–33, p. 22. 31 'RabbitRemix',www.ekac.org, ...

Author: Victoria Dickenson

Publisher: Reaktion Books

ISBN: 9781780232164

Category: Nature

Page: 224

View: 517

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From Benjamin Bunny to Peter Cottontail, the Velveteen Rabbit to the Flopsy Bunnies, the Rabbit of Caerbannog to Bugs Bunny and Roger Rabbit, the winsome long-eared animal is a permanent fixture of our childhoods. We know rabbits for their place in our stories, myths, and legends, and also for how they helped us learn to tie our shoes. In this richly illustrated book, Victoria Dickenson explores the natural and cultural history of the most familiar of the lagomorphs. Tracing the history of the species, Dickenson brings to life the giant extinct rabbits of Minorca and the tiny endangered Volcano rabbits of Mexico while focusing on the European rabbit. She explains how humans became this particular rabbit’s greatest predator, coveting its fur and flesh, and how they distributed rabbits to such far-flung places as New Zealand and Australia to provide food and sport for settlers. Dickenson also examines the paradox of the rabbit as prey and trickster who outwits all rivals, as cuddly companion for children and symbol of unbridled animal passion. She looks at the use of the rabbit’s foot to charm away evil, celebrates the Year of the Rabbit, and discovers the Jade Moon Rabbit, who lives on the moon. Hopping from B’rer Rabbit to the Energizer Bunny, Rabbit is the perfect gift for anyone who loves these intelligent, adorable creatures.

Essentials of Laboratory Animal Science Principles and Practices

In: Houdebine LM, Fan J (eds) Rabbit biotechnology: rabbit genomics, transgenesis, cloning and models. Springer, Netherlands, pp 49–63. https://doi.org/10.1007/978-90-481-2227-1 6. Peng X, Knouse JA, Hernon KM (2015) Rabbit models for ...

Author: P. Nagarajan

Publisher: Springer Nature

ISBN: 9789811609879

Category: Science

Page: 806

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This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

Biotechnology Plant biotechnology animal cell culture immunobiotechnology

Load the left trough with goat anti - rabbit whole serum and the right trough with goat anti - rabbit IgG . 13. Place the gel in a closed humidifying chamber containing moistened paper towels and allow diffusion to take place over a 24 ...

Author: Jack G. Chirikjian

Publisher: Jones & Bartlett Learning

ISBN: 0867208953

Category: Science

Page: 220

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Vol. I: The work presented in these two volumes is the collaborative effort of over twenty undergraduate science faculty, whose common goal was to develop a text of unique and flexible laboratory activities focusing on the theory and practice of biotechnology for undergraduate students. The books are designed to provide flexibility for easy integration into any course in the life sciences with an experimental emphasis.

Principles of Cloning

Chapter 18 Cloning of Rabbits Connecticut, CT, USA Chapter Outline INTRODUCTION Introduction 227 Background of Rabbit Embryo Embryology 228 Historical Background of Rabbit Biotechnology 228 Embryonic and Fetal Development in Rabbits 228 ...

Author: Jose Cibelli

Publisher: Academic Press

ISBN: 9780123865427

Category: Science

Page: 572

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Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning technique, including the first demonstration that cloning works in differentiated cells done by the Recipient of the 2012 Nobel Prize for Physiology or Medicine – Dr John Gurdon; the cloning of the first mammal from a somatic cell – Drs Keith Campbell and Ian Wilmut; the demonstration that cloning can reset the biological clock - Drs Michael West and Robert Lanza; the demonstration that a terminally differentiated cell can give rise to a whole new individual – Dr Rudolf Jaenisch and the cloning of the first transgenic bovine from a differentiated cell – Dr Jose Cibelli. The majority of the contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. First and most comprehensive book on animal cloning, 100% revised Describes an in-depth analysis of current limitations of the technology and research areas to explore Offers cloning applications on basic biology, agriculture, biotechnology, and medicine

Pharmaceutical Biotechnology

The test includes measuring a rise in rabbit temperature after intravenous administration of a test solution (USP, 2017; ANVISA, 2010). The LPS test in rabbits was first introduced into the United States Pharmacopoeia (USP XII) in 1942.

Author: Adalberto Pessoa

Publisher: CRC Press

ISBN: 9781000399844

Category: Medical

Page: 400

View: 843

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Pharmaceutical Biotechnology: A Focus on Industrial Application covers the development of new biopharmaceuticals as well as the improvement of those being produced. The main purpose is to provide background and concepts related to pharmaceutical biotechnology, together with an industrial perspective. This is a comprehensive text for undergraduates, graduates and academics in biochemistry, pharmacology and biopharmaceutics, as well as professionals working on the interdisciplinary field of pharmaceutical biotechnology. Written with educators in mind, this book provides teachers with background material to enhance their classes and offers students and other readers an easy-to-read text that examines the step-by-step stages of the development of new biopharmaceuticals. Features: Discusses specific points of great current relevance in relation to new processes as well as traditional processes Addresses the main unitary operations used in the biopharmaceutical industry such as upstream and downstream Includes chapters that allow a broad evaluation of the production process Dr. Adalberto Pessoa Jr. is Full Professor at the School of Pharmaceutical Sciences of the University of São Paulo and Visiting Senior Professor at King’s College London. He has experience in enzyme and fermentation technology and in the purification processes of biotechnological products such as liquid–liquid extraction, cross-flow filtration and chromatography of interest to the pharmaceutical and food industries. Dr. Michele Vitolo is Full Professor at the School of Pharmaceutical Sciences of the University of São Paulo. He has experience in enzyme technology, in immobilization techniques (aiming the reuse of the biocatalyst) and in the operation of membrane reactors for obtaining biotechnological products of interest to the pharmaceutical, chemical and food industries. Dr. Paul F. Long is Professor of Biotechnology at King's College London and Visiting International Research Professor at the University of São Paulo. He is a microbiologist by training and his research uses a combination of bioinformatics, laboratory and field studies to discover new medicines from nature, particularly from the marine environment.