Protein Nanotechnology

14 Construction of Ordered Protein Arrays Jarrod Clark, Taras Shevchuk, Piotr M. Swiderski, Rajesh Dabur, Laura E. Crocitto, Yaroslav I. Buryanov, and Steven S. Smith Summary Artificially ordered protein arrays provide a facile approach ...

Author: Tuan Vo-Dinh

Publisher: Springer Science & Business Media

ISBN: 9781592598588

Category: Science

Page: 466

View: 385


Leading experts in nanobiotechnology comprehensively review the most recent advances in instrumentation and methodology, as well as their applications in genomics and proteomics. The authors provide a wide variety of techniques and methods for dealing with protein functions and structures at the nanoscale level, including nanostructured systems, nanomaterials, carbon nanotubes and nanowires, optical nanosensors, and nanoelectrodes. Among the highlights are techniques for the in vivo tracking of biochemical processes using fluorescent molecular probes and nanosensors, and the exploration of biochemical processes and submicroscopic structures of living cells at unprecedented resolutions using near-field optics. Also discussed is the development of nanocarrier methodology for the targeted delivery of drugs whose shells are conjugated with antibodies for targeting specific antigens.

barrel Channel Proteins as Tools in Nanotechnology

The protein based nano-material development is backed up by the vast progress that has been made in the molecular biology and biotechnology field, specifically in the development and optimization of advanced genetic engineering ...

Author: Marco Fioroni

Publisher: Springer Science & Business Media

ISBN: 9789400774292

Category: Science

Page: 168

View: 440


ß-barrel outer membrane channel proteins (OMP) are useful as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. It gives a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel will be outlined. An exhaustive description of the scientific strategy, including protein selection, analytical methods and “in-silico” tools to support the planning of protein modifications for a targeted application, consideration on the production of a custom made OMP, and an overview on technological applications including membrane/polymersome technology, will be provided.

Protein based Engineered Nanostructures

Advent of protein engineering techniques and algorithms to predict sequencestructure-function of proteins yielded many de novo proteins designed specifically for nanotechnology applications. Protein nanotechnology is an emerging field ...

Author: Aitziber L. Cortajarena

Publisher: Springer

ISBN: 9783319391960

Category: Science

Page: 286

View: 565


This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using “bottom-up” strategies. This book addresses in an integrated manner all the critical aspects that need to be understood and considered to design the next generation of nano-bio assemblies. The book covers first the fundamentals of the design and features of the protein building blocks and their self-assembly illustrating some of the most relevant examples of nanostructural design. Finally, the book contains a section dedicated to demonstrated applications of these novel bioinspired nanostructures in different fields from hybrid nanomaterials to regenerative medicine. This book provides a comprehensive updated review of this rapidly evolving field.

Nano inspired Biosensors for Protein Assay with Clinical Applications

Aguide for understanding nanotechnology for biosensors and its applications for protein analysis and Clinical diagnosis • Provides a single source of information on the latest developments in the field of biosensors for protein analysis ...

Author: Genxi Li

Publisher: Elsevier

ISBN: 9780128150542

Category: Science

Page: 378

View: 518


Nano-inspired Biosensors for Protein Assay with Clinical Applications introduces the latest developments in nano-inspired biosensing, helping readers understand both the fundamentals and frontiers in this rapidly advancing field. In recent decades, there has been increased interest in nano-inspired biosensors for clinical application. Proteins, e.g. antigen-antibody, tumor markers and enzymes are the most important target in disease diagnosis, and a variety of biosensing techniques and strategies have been developed for protein assay. This book brings together all the current literature on the most recent advances of protein analysis and new methodologies in designing new kinds of biosensors for clinical diagnostic use. Provides a single source of information on the latest developments in the field of biosensors for protein analysis and clinical diagnosis Focuses on biosensors fabricated with nanomaterials and nanotechnology Gives detailed methodologies for designing and fabricating nano-inspired biosensors

Nanotechnology Characterization Tools for Environment Health and Safety

Nanoscale 8:6948–6957 Casals E, Pfaller T, Duschl A, Oostingh GJ, Puntes V (2010) Time evolution of the nanoparticle protein corona. ACS Nano 4:3623–3632 Tenzer S et al (2013) Rapid formation of plasma protein corona critically affects ...

Author: Challa S.S.R. Kumar

Publisher: Springer Nature

ISBN: 9783662596005

Category: Technology & Engineering

Page: 353

View: 152


Tenth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Environment, Health, and Safety. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

RNA Nanotechnology and Therapeutics

Structure by design: from single proteins and their building blocks to nanostructures. ... The polycomb group protein EZH2 is involved in progression of prostate cancer. ... Protein nanotechnology: the new frontier in biosciences.

Author: Peixuan Guo

Publisher: CRC Press

ISBN: 9781000552737

Category: Medical

Page: 644

View: 206


Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. In addition, the text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, immunorecognition of RNA nanomaterials, RNA chemistry for nanoparticle synthesis, and conjugation and labeling. Presents the latest research and discoveries in RNA nanotechnology Features contributions from world-class experts in the field Covers RNA nanoparticles in therapeutics Describes self-assembled RNA nanoparticles

Food Nanoscience and Nanotechnology

Being able to electrospin proteins in a food-grade way can open a new route toward nutritionally and texturally appealing meat replacers. Proteins are notoriously difficult to electrospin, mainly because of their complex secondary and ...

Author: Humberto Hernández-Sánchez

Publisher: Springer

ISBN: 9783319135960

Category: Technology & Engineering

Page: 300

View: 485


Nanoscience and nanotechnology have had a great impact on the food industry. They have increased the nutritional and functional properties of a number of food products and have aided in food preservation through the addition of antimicrobials or the reduction of water activity. These and many other applications have emerged in recent years to transform food science and technology. This book proposes to look at some of these applications and their effect on food production and innovation.

Perspectives in Micro and Nanotechnology for Biomedical Applications

... Biswas et al. for protein delivery consisted of a nano capsule crosslinked by bisacrylated peptides with specific ... The researchers delivered both cytosolic and nuclear proteins in their active forms to different cell lines using ...

Author: Juliana M Chan

Publisher: World Scientific

ISBN: 9781783269624

Category: Science

Page: 312

View: 448


Perspectives in Micro- and Nanotechnology for Biomedical Applications is an exciting new book that takes readers inside the fast-paced world of biomedical sciences fueled by advancements in nanotechnology, polymer chemistry and pharmacology. Guided by biotech researchers Chenjie Xu and Juliana Chan, an international ensemble of leading experts in the field cover topics ranging from classical chemical tools to nanoparticles as imaging probes and drug carriers, and combinatorial screens for new lipids and polymers. At the microscale it discusses advancements in hydrogels and platform technologies such as cell ghosts. This book provides a broad perspective into the basic principles and applications of today's most promising micro- and nanotechnologies, and is an up-to-date reference book for researchers. It is also suitable for undergraduate and graduate students, patent lawyers and investors who are interested in the latest innovations taking place in the biomedical sciences, many of which may dramatically improve the lives of millions of people.

Microbial Nanotechnology

CCMV comprises 180 subunits of coat protein that contains 190 amino acids (Ma et al. 2012). The CCMV VLPs are a multifunctional nano platform used in the effective diagnosis and treatment for several viral and bacterial infections (Tang ...

Author: Mohammad Azam Ansari

Publisher: Springer Nature

ISBN: 9789811619236

Category: Industrial microbiology


View: 343


This book introduces the principles and mechanisms of the biological synthesis of nanoparticles from microorganisms, including bacteria, fungi, viruses, algae, and protozoans. It presents optimization processes for synthesis of microbes-mediated nanoparticles. The book also reviews the industrial and agricultural applications of microbially-synthesized nanoparticles. It also presents the medical applications of green nanoparticles, such as treating multidrug-resistant pathogens and cancer treatment. Further, it examines the advantages and prospects for the synthesis of nanoparticles by microorganisms. Lastly, it also presents the utilization of microbial-synthesized nanoparticles in the bioremediation of heavy metals.