Principles and Practice of Systematic Reviews and Meta Analysis

Mangesh Deshmukh Abstract Systematic reviews involve a sequence of decisions and assumptions ranging from the definition of a particular variable and use of statistical methods to the type of model chosen for meta-analysis.

Author: Sanjay Patole

Publisher: Springer Nature

ISBN: 9783030719210

Category: Medical

Page: 189

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Evidence based medicine is at the core of modern medicine. It involves the integration of individual clinical expertise with the best available clinical evidence from systematic research and patient's values and expectations. Systematic reviews offer a summary of the best available evidence. They are the most reliable and comprehensive statement about what works. Written by clinical academics from Australia, UK, USA, and Switzerland, this contributed volume introduces the readers to the principles and practice of systematic reviews and meta-analysis. It covers the various steps involved in systematic reviews including development of a focused question and the strategy for conducting a comprehensive literature search, identifying studies addressing the underlying question, assessment of heterogeneity and the risk of bias in the included studies, data extraction, and the approach to meta-analysis. Crucial issues such as selecting the model for meta-analysis, generating and interpreting forest plots, assessing the risk of publication bias, cautions in the interpretation of subgroup and sensitivity analyses, rating certainty of the evidence using GRADE guideline, and standardized reporting of meta-analysis (PRISMA) are covered in detail. Every attempt is made to keep the narrative simple and clear. Mathematical formulae are avoided as much as possible. While the focus of this book is on systematic reviews and meta-analyses of randomised controlled trials (RCTs), the gold standard of clinical research, the essentials of systematic reviews of non-RCTs, diagnostic test accuracy studies, animal studies, individual participant data meta-analysis, and network meta-analysis are also covered. Readers from all faculties of medicine will enjoy this comprehensive and reader friendly book to understand the principles and practice of systematic reviews and meta-analysis for guiding their clinical practice and research.

Principles and Practice of Surgery E Book

A meta-analysis is a statistical method of quantitatively combining data from multiple studies to give an overall summary and estimate of the effect studied. It is usually performed as part of a systematic review.

Author: O. James Garden

Publisher: Elsevier Health Sciences

ISBN: 9780702068577

Category: Medical

Page: 584

View: 536

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Principles and Practice of Surgery is the surgical companion textbook to the international medical bestseller Davidson’s Principles and Practice of Medicine. It is a comprehensive textbook for both the surgical student and trainee, guiding the reader through key core surgical topics which are encountered throughout an integrated medical curriculum as well as in subsequent clinical practice. Although sharing the same format and style as Davidson’s Principles and Practice of Medicine, this text is complete in itself, thus enabling the student to appreciate both the medical and surgical implications of diseases encountered in surgical wards. A three-section textbook of surgical principles and regional clinical surgery. The textbook presents a comprehensive account of international surgical practice, taking into account variations in the disease patterns and management approaches throughout the world. Superbly presented with line drawings, high quality radiographic images and colour photographs. Presented in similar form to its sister textbook Davidson’s Principles and Practice of Medicine. Full online and ebook version available as part of Student Consult. A new chapter on Evidence-based practice and professional development. An expanded chapter on Surgical preparation includes an account of the main issues surrounding day case surgery. A new International Advisory Board based in India, South Africa, South-east Asia and Europe has advised throughout on the structure and content of the book. Consequently the text has been updated to reflect changes in understanding, evidence and practice, and to keep the contents in line with undergraduate and postgraduate surgical curricula The evidence-based revision boxes that focus on major international guidelines have been thoroughly updated. The text on tropical conditions such as tropical pancreatitis, tuberculosis affecting the various organ systems and filarial lymphoedema has been expanded. Innovations useful in the practice of surgery in resource-poor environments have been included. The text gives a global emphasis on epidemiological and cultural issues such as problems associated with directed transfusion of blood products from first degree relatives, the issues of informed consent and patient autonomy. A comparison of SI and non-SI reference ranges for commonly used laboratory values has been added.

Creasy and Resnik s Maternal Fetal Medicine Principles and Practice E Book

Preferred Reporting Items for Systematic Reviews and MetaAnalyses: The PRISMA Statement. ... To overcome these challenges, good practice recommends performing subgroup analyses in select prespecified groups based on a biologically ...

Author: Robert Resnik

Publisher: Elsevier Health Sciences

ISBN: 9780323568913

Category: Medical

Page: 1859

View: 109

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Long recognized as the authoritative leader in the field, Creasy and Resnik's Maternal-Fetal Medicine, 8th Edition, continues to provide the latest evidence-based guidelines for obstetric and neonatal management, helping you minimize complications and offer patients the best possible care. Written by renowned experts in obstetrics, gynecology, and perinatology, this comprehensive resource has been thoroughly updated and reflects new information in every area, including recent tremendous advances in genetics, imaging, and more. Focuses on complicated obstetric issues, highlighting the most commonly encountered anomalies and providing clear guidelines for obstetric and neonatal management. Offers comprehensive updates on rapidly changing topics, including a completely revised section on genetics and genetic technology for prenatal diagnoses, as well as an expanded imaging section on abdominal, urogenital, and skeletal imaging. Includes four new chapters: Molecular Genetic Technology, MRI in Obstetrical Imaging, Obesity in Pregnancy, and Pregnancy as a Window to Future Health. Features numerous flow charts for quick access to diagnosis and treatment protocols and to clarify complex material. Presents the knowledge and expertise of new editors Dr. Joshua Copel, an expert in the field of fetal therapy who has pioneered new diagnostic techniques for unborn patients and their mothers, and Dr. Robert Silver, a leader in the maternal-fetal medicine community.

Mandell Douglas and Bennett s Principles and Practice of Infectious Diseases

Differential time to 153. Snyder SR, Favoretto AM, Baetz RA, et al. Effectiveness of practices to reduce blood culture contamination: a Labora- tory Medicine Best Practices systematic review and meta- analysis. Clin Biochem.

Author: John E. Bennett, MD, MACP

Publisher: Elsevier Health Sciences

ISBN: 9781455748013

Category: Medical

Page: 3904

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After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.

Principles and Practice of Clinical Trials

Available from https://www. equator-network.org/?post_type=eq_guidelines&eq_guidelines_study_design=systematicreviews-and-meta-analyses&eq_guidelines_clinical_specialty=0&eq_guidelines_report_ section=0&s=+. Accessed 9 Mar 2020 Garner P ...

Author: Steven Piantadosi

Publisher: Springer Nature

ISBN: 9783319526362

Category:

Page:

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PDQ Evidence based Principles and Practice

Meta-analysis.sh . Psycinfo.sh . Pubmed.sh . Qualitative studie.sh . Systematic review.sh . Systematic review.pt . Indexing Example 4 : Meta - analysis of Meta - analyses Grissom , RJ . The magical number 7 +/- 2 : Meta - meta ...

Author: Ann McKibbon

Publisher: PMPH-USA

ISBN: 1607950065

Category: Medical

Page: 304

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PDQ Evidence-Based Principles and Practice addresses the concepts of evidence based health care in a gentle, non-technical manner. One of its two major purposes is to provide a background to understand health care research and how best to evaluate and apply new research findings in health. The audience is librarians and other information professionals who work with health professionals. Clinicians seeking a gentle approach to working with health research findings will also benefit. In addition the book outlines how best to identify important studies in health care published in the large bibliographic databases such as MEDLINE and the Internet. Readers found the first edition useful in understanding health research and seeking this information. The second edition strengthened both purposes. It also adds 4 new chapters to the existing 9 that cover new areas of understanding and producing health research. All chapters from the previous edition have been revised. Several new chapters (hot topics) have been added: Clinical Prediction Guides, Decision Analyses, Differential Diagnosis and Disease Manifestation, and Health Technology Assessment. Proven and validated search strategies for use in the large electronic biomedical databases have been included in the edition. Lists of possible searching terms have been enhanced and enlarged. We have also added an appendix of terms used in the book using plain language descriptions as well as searching tips and sites for retrieval in the categories of health research . This book helps the reader develop optimal, effective MEDLINE search strategies. It offers step-by-step suggestions for retrieving sound clinical studies on the etiology, prognosis, diagnosis, prevention, and management of disorders encountered in adult general medicine. Key Features Gentle, non-technical introduction to the concepts of evidence based health care Provides a background to understanding health care research Provides a guide for evaluating health care research Provides searching tips and techniques to enhance and speed searching for health care research in the large electronic databases Collects searching terms effective for retrieval of clinically important material from MEDLINE and related databases

Cochrane Handbook for Systematic Reviews of Interventions

The revised edition of the Handbook offers the only guide on how to conduct, report and maintain a Cochrane Review The second edition of The Cochrane Handbook for Systematic Reviews of Interventions contains essential guidance for preparing ...

Author: Julian P. T. Higgins

Publisher: John Wiley & Sons

ISBN: 9781119536628

Category: Medical

Page: 739

View: 574

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The revised edition of the Handbook offers the only guide on how to conduct, report and maintain a Cochrane Review The second edition of The Cochrane Handbook for Systematic Reviews of Interventions contains essential guidance for preparing and maintaining Cochrane Reviews of the effects of health interventions. Designed to be an accessible resource, the Handbook will also be of interest to anyone undertaking systematic reviews of interventions outside Cochrane, and many of the principles and methods presented are appropriate for systematic reviews addressing research questions other than effects of interventions. This fully updated edition contains extensive new material on systematic review methods addressing a wide-range of topics including network meta-analysis, equity, complex interventions, narrative synthesis, and automation. Also new to this edition, integrated throughout the Handbook, is the set of standards Cochrane expects its reviews to meet. Written for review authors, editors, trainers and others with an interest in Cochrane Reviews, the second edition of The Cochrane Handbook for Systematic Reviews of Interventions continues to offer an invaluable resource for understanding the role of systematic reviews, critically appraising health research studies and conducting reviews.

Principles and Practice of Hospital Medicine 2nd Edition

SYSTEMATIC REVIEWS □ INTRODUCTION There are four major overviews, and they include narrative reviews, systematic reviews, meta-analysis, and guidelines. They represent the highest quality of evidence on the quality pyramid as they ...

Author: Sylvia C. McKean

Publisher: McGraw Hill Professional

ISBN: 9780071843140

Category: Medical

Page: 2265

View: 932

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The leading textbook of hospital medicine – completely updated to reflect today’s challenges A Doody’s Core Title for 2021! Since its publication in 2012, Principles and Practice of Hospital Medicine, Second Edition has become the field’s premier resource. Comprehensive, authoritative, and practical, this landmark text provides a solid grounding in clinical, organizational, and administrative areas central to the practice of hospital medicine. The Second Edition has been completely updated to reflect the evolving practice responsibilities of hospitalists. Examples include value-based medicine, expanded surgical content, bedside clinical reasoning, and a new segment devoted to rehabilitation and skilled nursing care. This edition also features a more accessible and streamlined full-color design enriched by more than 600 illustrations. Each clinical chapter opens with boxed Key Clinical Questions that are addressed in the text and summarized in hundreds of tables. Case studies demonstrate how to apply this information specifically to the management of hospitalized patients. Representing the expertise of more than two hundred renowned contributors, Principles and Practice of Hospital Medicine, Second Edition is logically divided into six sections: The Specialty of Hospital Medicine and Systems of Care Medical Consultation Rehabilitation and Skilled Nursing Care The Approach to the Patient at the Bedside Diagnostic Testing and Procedures Clinical Conditions in the Inpatient Setting Principles and Practice of Hospital Medicine, Second Edition is essential reading for clinicians who strive to optimize inpatient care and sharpen their leadership skills.

How To Do A Systematic Literature Review In Nursing A Step By Step Guide

To facilitate the review a number of blank forms are presented for the reader to copy and complete in relation to the topic which they are pursuing ... I would wholly recommend this text.

Author: Bettany-Saltikov, Josette

Publisher: McGraw-Hill Education (UK)

ISBN: 9780335242276

Category: Medical

Page: 173

View: 982

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"This is an excellent book which explains clearly the principles and practice of systematic reviews. The order of contents is logical, information is easy to find and the contents are written for a wide audience from student to practitioner. There are copious examples and illustrations and these should inspire confidence in the novice and remind the expert what the essential features of a good systematic review are. This book should be on every undergraduate and postgraduate reading list for courses on research methods." Roger Watson, Professor of Nursing, The University of Hull, UK "This book provides a clear and concise guide for students to produce a systematic review of evidence in health care ... The material is presented as a logical series of steps starting with developing a focussed question up to completing the review and disseminating its findings ... To facilitate the review a number of blank forms are presented for the reader to copy and complete in relation to the topic which they are pursuing ... I would wholly recommend this text." Ian Atkinson, previously Senior Lecturer in Research Methods & Assistant Editor Journal of Clinical Nursing Does the idea of writing a systematic literature review feel daunting? Are you struggling to work out where to begin? By walking you carefully through the entire process from start to finish and breaking the task down into manageable steps, this book is the perfect workbook companion for students undertaking their first literature review for study or clinical practice improvement. Co-published with the Nursing Standard, this handy book: Goes into detail about the precise and practical steps required to carry out a systematic literature review Uses a workbook format, with 3 running examples that you can work through gradually as you carry out your review Offers suggestions and tips to help you write up your own review Features useful templates to help you stay organised and includes case-studies to identify good practice Highlights the pitfalls to avoid Written in an engaging, conversational style with clear explanations throughout, How to do a Systematic Literature Review in Nursing is invaluable reading for all nursing students as well as other healthcare professionals.

Evidence based Otitis Media

CHAPTER 4 Meta - analysis and Systematic Literature Review Richard M. Rosenfeld , MD , MPH Knowledge is a process of piling ... and future research agendas.27 This chapter introduces the principles and practice of meta - analysis in the ...

Author: Richard M. Rosenfeld

Publisher: PMPH-USA

ISBN: 1550092545

Category: Medical

Page: 552

View: 481

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Evidence-Based Otitis Media offers one-stop shopping for the best current evidence to guide management decisions at the individual, organizational, and societal levels. This text details the importance of evidence-based data in interpreting the ever-enlarging body of literature on otitis media. The editors have assembled an impressive group of experts on all aspects of otitis media and addressed comprehensively many issues related to methodology, clinical management, and consequences of this disease. The eight chapters comprising the methodology section provide the necessary background and detail to allow physicians and other health professionals to understand and appreciate the value of evidence-based medicine. Updates include: the incorporation of new original research, systemic reviews, and evidence reports to existing chapters. New chapter topics include: evidence-based medicine, professional evidence reports, molecular and translational research, complementary and alternative medicine, bacteriologic efficacy of antimicrobials, vaccine prevention, international management perspectives, meta-analysis of speech and language sequelae, suppurative complications, host susceptibility to sequelae, and judicious use of systemic and topical antimicrobials. FEATURES: *Maturation of evidence-based medicine as a foundation for clinical care is reflected throughout the text. *Extensive evidence tables summarize study characteristics and quantitative outcomes for clinically relevant endpoints *Internationally distinguished contributors selected based on both their clinical expertise and their ability to write for an evidence-based text