Nickel and Human Health

Iron , like magnesium and zinc , prevents some toxic effects of nickel in various organisms ; interaction of these two metals in biological systems is apparently competitive , but its exact nature remains unknown ( Nielsen , 1980 ) .

Author: Evert Nieboer

Publisher: Wiley-Interscience

ISBN: UVA:X002428556

Category: Science

Page: 680

View: 120


As versatile as it is durable, nickel is the indispensable metal of coins, plating, ceramics, and countless alloys. The significance of the metal—particularly its environmental and occupational health effects—has been the subject of widespread scientific research and debate. Nickel and Human Health: Current Perspectives is a definitive compendium of the research being conducted internationally in nickel toxicology. Featuring the work of preeminent researchers, including one of the "fathers" of nickel toxicology, William Sunderman, Sr., this landmark volume systematically examines such key issues as the biological utilization of nickel, toxicokinetics in humans, occupational exposure and biological monitoring of workers, hypersensitivity and immunotoxicology, clinical aspects of nickel carbonyl poisoning, and experimental nickel carcinogenesis. It also presents an historical perspective of nickel toxicology, as well as a summary of the worldwide epidemiological evidence for the occurrence of nickel-induced nasal and lung cancers among nickel workers. Its 50 chapters, each devoted to a separate research topic, reflect the collective effort of contributors to IUPAC’s Fourth International Conference on Nickel Metabolism and Toxicology. Updated to reflect up-to-the-minute advances, the assembled work presents an invaluable far-sighted, multidisciplinary look at the subject that should prove essential for students, researchers, physicians, and allied health professionals as well as regulatory specialists in universities, research institutes, industry and government who are concerned about nickel toxicology and related health effects.

Trace Elements in Terrestrial Environments

6.3 Effects of Nickel on Human Health No toxicological incidents from Ni and its salts been recorded in the early 1900s ( Sunderman , 1992 ) . In fact , Ni salts had some medicinal value for the treatment of epilepsy , chorea , migraine ...

Author: Domy C. Adriano

Publisher: Springer Science & Business Media

ISBN: 0387986782

Category: Science

Page: 888

View: 724


A comprehensive reference handbook on the important aspects of trace elements in the land environment. Each chapter addresses a particular element and gives a general introduction to their role in the environment, where they come from, and their biogeochemical cycles. In addition to a complete updating of each of the element chapters, this new edition has new chapters devoted to aluminum and iron, soil contamination, remediation and trace elements in aquatic ecosystems. In short, an essential resource for environmental scientists and chemists, regulators and policy makers.

PHEs Environment and Human Health

Potentially harmful elements in the environment and the impact on human health Claudio Bini, Jaume Bech. 2.6. Nickel. Nickel is a ubiquitous and nutritionally essential nutrient for plants, animals and micro-organisms.

Author: Claudio Bini

Publisher: Springer

ISBN: 9789401789653

Category: Science

Page: 467

View: 197


This book is dedicated to the occurrence and behaviour of PHEs in the different compartments of the environment, with special reference to soil. Current studies of PHEs in ecosystems have indicated that many industrial areas near urban agglomerates, abandoned or active mines, major road systems and ultimately also agricultural land act as sources and at the same time sinks, of PHEs and large amounts of metals are recycled or dispersed in the environment, posing severe concerns to human health. Thanks to the collaboration of numerous colleagues, the book outlines the state of art in PHEs research in several countries and is enforced with case studies and enriched with new data, not published elsewhere. The book will provide to Stakeholders (both Scientists Professionals and Public Administrators) and also to non-specialists a lot of data on the concentrations of metals in soils and the environment and the critical levels so far established, in the perspective to improve the environmental quality and the human safety.

Elemental Speciation in Human Health Risk Assessment

P. Apostoli, World Health Organization, United Nations Environment Programme, International Labour Organisation. 8.9.3 Nickel Nickel and its compounds have numerous industrial applications, including the production of steels, alloys, ...

Author: P. Apostoli

Publisher: World Health Organization

ISBN: 9789241572347

Category: Medical

Page: 257

View: 385


Definitions of species and speciation - - Strructural aspects of speciation - - Analytical techniques and methodology - - Bioaccessibility and bioavailability - - Toxicokinetics and biological monitoring - - Molecular and cellular mechanisms of metal toxicity - - Health effects - - Conclusions and recommendations.

Carcinogenicity of Inorganic Substances

Health Perspect., 92,93–104. International Agency For Research On Cancer (1990) 'IARC Monographs on the evaluation of Carcinogenic Risks to Humans. Chromium, Nickel and Welding'. Vol. 49, IARC, Lyon. Horiguchi, S., Morinaga, K., Endo, ...

Author: J H Duffus

Publisher: Woodhead Publishing

ISBN: 9781782424413

Category: Technology & Engineering

Page: 296

View: 819


Focuses on the state of scientific knowledge about the carcinogenicity of metals, their compounds and other inorganic substances. It provides a valuable guide for chemists involved in risk assessment, health and safety and toxicology.

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Shi, Z. 1994a. Nickel carbonyl: Toxicity and human health. Sci. Total Environ. 148(23):293-298. Shi, Z. 1994b. Study on lung function and blood gas analysis of nickel carbonyl workers. Sci. Total Environ. 148(2-3):299-301.

Author: National Research Council

Publisher: National Academies Press

ISBN: 030917774X

Category: Science

Page: 320

View: 754


This book is the sixth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and includes AEGLs for chemicals such as ammonia, nickel carbonyl and phosphine, among others. At the request of the Department of Defense, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for 12 new chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies such as accidental or intentional chemical releases in the community, the workplace, transportation, the military, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts.

Annual Report

Nickel in human health : current perspectives . ... Magnesium counteracts nickel - induced suppression of T - lymphocyte response to concanavalin A. Magnesium 1988 ; 7 : 166-72 . ; Kasprzak KS , Kovatch RM , Poirier LA .

Author: National Cancer Institute (U.S.). Division of Cancer Etiology



Category: Cancer


View: 353


Custer National Forest N F Stillwater Mine Expansion 2000 TPD

Manganese is not known to adversely affect aquatic organisms . The surface water standard of 0.05 mg / L is based on human health and is primarily intended to prevent staining and objectional tastes . Nickel . Nickel concentrations in ...



ISBN: NWU:35556030573786



View: 936


Eisler s Encyclopedia of Environmentally Hazardous Priority Chemicals

Studies that compare the toxicokinetics of humans and animals concurrently could be helpful in determining which species of animal is the most appropriate model for assessing the effects of nickel in human health.

Author: Ronald Eisler

Publisher: Elsevier

ISBN: 0080547079

Category: Technology & Engineering

Page: 986

View: 938


Thousands of inorganic and organic chemicals and their metabolites enter the biosphere daily as a direct result of human activities. Many of these chemicals have serious consequences on sensitive species of natural resources, crops, livestock, and public health. The most hazardous of these were identified by a panel of environmental specialists from the U.S. Fish and Wildlife Service; these chemicals are the focus of this encyclopedia. For each priority group of chemicals, information is presented on sources, uses, physical and chemical properties, tissue concentrations in field collections and their significance, lethal and sublethal effects under controlled conditions. This includes effects on survival, growth, reproduction, metabolism, carcinogenicity, teratogenicity, and mutagenicity - and proposed regulatory criteria for the protection of sensitive natural resources, crops, livestock, and human health. Taxonomic groups of natural resources covered include terrestrial and aquatic plants and invertebrates, fishes, amphibians, reptiles, birds, and mammals. * The only product that centers on the most hazardous environmental chemicals to sensitive natural resources * The only single volume compendium on the subject, allowing ease in consulting * Written by a noted national and international authority on chemical risk assessment to living organisms

Information Resources in Toxicology

Lauffer, R. B. (Ed.) (1992) Iron and Human Disease CRC Press, Boca Raton, FL Topics discussed include chemistry and ... Nieboer, E., and Nriagu, J. O. (Eds.) (1992) Nickel and Human Health: Current Perspectives Wiley, New York Volume 25 ...

Author: Philip Wexler

Publisher: Academic Press

ISBN: 9780127447704

Category: Medical

Page: 953

View: 670


History: -- K.D. Watson, P. Wexler, and J. Everitt. -- Highlights in the History of Toxicology. -- Selected References in the History of Toxicology. -- A Historical Perspective of Toxicology Information Systems. -- Books and Special Documents: -- G.L. Kennedy, Jr., P. Wexler, N.S. Selzer, and L.A. Malley. -- General Texts. -- Analytical Toxicology. -- Animals in Research. -- Biomonitoring/Biomarkers. -- Biotechnology. -- Biotoxins. -- Cancer. -- Chemical Compendia. -- Chemical--Cosmetics and Other Consumer. -- Products. -- Chemical--Drugs. -- Chemical--Dust and Fibers. -- Chemical--Metals. -- Chemicals--Pesticides -- Chemicals--Solvents. -- Chemical--Selected Chemicals. -- Clinical Toxicology. -- Developmental and Reproductive Toxicology. -- Environmental Toxicology--General. -- Environmental Toxicology-- Aquatic. -- Environmental Toxicology--Atmospheric. -- Environmental Toxicology--Hazardous Waste. -- Environmental Toxicology--Terrestrial. -- Environmental Toxicology--Wildlife. -- Ep ...