Lipid Biochemistry

Lipid Biochemistry, fifth edition has been largely re-written in a user-friendly way, with chapters containing special interest topic boxes, summary points and lists of suggested reading, further enhancing the accessibility and readability ...

Author: Michael I. Gurr

Publisher: John Wiley & Sons

ISBN: 9781405172707

Category: Medical

Page: 336

View: 456

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Since the publication of the first edition of this successful and popular book in 1970, the subject of lipid biochemistry has evolved greatly and this fifth up-to-date and comprehensive edition includes much new and exciting information. Lipid Biochemistry, fifth edition has been largely re-written in a user-friendly way, with chapters containing special interest topic boxes, summary points and lists of suggested reading, further enhancing the accessibility and readability of this excellent text. Contents include abbreviations and definitions used in the study of lipids, routine analytical methods, fatty acid structure and metabolism, dietary lipids and lipids as energy stores, lipid transport, lipids in cellular structures and the metabolism of structural lipids. The book provides a most comprehensive treatment of the subject, making it essential reading for all those working with or studying lipids. Upper level students of biochemistry, biology, clinical subjects, nutrition and food science will find the contents of this book invaluable as a study aid, as will postgraduates specializing in the topics covered in the book. Professionals working in research in academia and industry, including personnel involved in food and nutrition research, new product formulation, special diet formulation (including nutraceuticals and functional foods) and other clinical aspects will find a vast wealth of information within the book's pages. Michael Gurr was a Visiting Professor in Human Nutrition at the University of Reading, UK and at Oxford Brookes University, UK. John Harwood is a Professor of Biochemistry at the School of Biosciences, Cardiff University, UK. Keith Frayn is a Professor of Human Metabolism at the Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK.

Lipid Biochemistry An Introduction

In the preface to the Second edition, we made a prediction that many exciting developments would take place in the coming years that would change the face of a new edition.

Author: M. I. Gurr

Publisher: Springer Science & Business Media

ISBN: 9789400959071

Category: Science

Page: 248

View: 268

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In the preface to the Second edition, we made a prediction that many exciting developments would take place in the coming years that would change the face of a new edition. This has indeed been the case and the current edition reflects these new advances. Our picture of the structure of the fatty acid synthetase has changed dramatically, bringing a new concept in enzymology - the multicatalytic polypeptide chain. This new knowledge owes much to the exploitation of genetic mutants, the use of which is undoubtedly going to extend into many other areas of lipid biochemistry. An understanding of the control of lipid metabolism has also advanced considerably during the last decade and we have tried to reflect that here, although it will be some years before a truly integrated picture can be obtained. For this reason we have continued to deal with the control of particular aspects of lipid metabolism - fatty acids, triacylglycerols, lipoprotein- in the specific chapters but we can foresee the time when a chapter on the overall integration of lipid metabolism will be appropriate and feasible. As a particular example, the exciting new concepts of the control of cholesterol metabolism in specific tissues via the interaction of low density lipoproteins with cell surface receptors have been described in Chapter 6.

Biochemistry of Lipids Lipoproteins and Membranes

three categories – fatty acids, simple lipids and complex lipids. ... A detailed explanation of the technical aspects of lipid MS from one of the pioneers of the lipid biochemistry field, Robert Murphy (1993), provides insightful ...

Author: Neale Ridgway

Publisher: Elsevier

ISBN: 9780444634498

Category: Science

Page: 612

View: 508

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Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six, contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology. It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information. It is a valuable tool for advanced graduate students and researchers who are interested in exploring lipid biology in more detail, and includes overviews of lipid biology in both prokaryotes and eukaryotes, while also providing fundamental background on the subsequent descriptions of fatty acid synthesis, desaturation and elongation, and the pathways that lead the synthesis of complex phospholipids, sphingolipids, and their structural variants. Also covered are sections on how bioactive lipids are involved in cell signaling with an emphasis on disease implications and pathological consequences. Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry References from current literature will be included in each chapter to facilitate more in-depth study Key concepts are supported by figures and models to improve reader understanding Chapters provide historical perspective and current analysis of each topic

Lipid Biochemistry

Trends in Biochemical Sciences, 9, 453-456. Role of lipids in immunity Gurr, M.I. (1983) The role of lipids in the regulation of the immune system. Progress in Lipid Research, 22, 257-287. Johnson, P.V. (1985) Dietary lipids and ...

Author: Michael Ian Gurr

Publisher: Kluwer Academic Pub

ISBN: UOM:39015019482325

Category: Science

Page: 406

View: 497

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Lipids can usually be extracted easily from tissues by making use of their hydrophobic characteristics. However, such extractions yield a complex mixture of different lipid classes which have to be purified further for quantitative analysis. Moreover, the crude lipid extract will be contami nated by other hydrophobic molecules, e.g. by intrinsic membrane proteins. Of the various types of separation processes, thin layer and column chromatography are most useful for intact lipids. High performance liquid chromatography (HPLC) is also rapidly becoming more popular, especially for the fractionation of molecular species of a given lipid class. The most powerful tool for quantitation of the majority of lipids is gas liquid chromatography (GLC). The method is very sensitive and, if adapted with capillary columns, can provide information with regard to such subtle features as the position or configuration of substitutions along acyl chains. By coupling GLC or HPLC to a radioactivity detector, then the techniques are also very useful for metabolic measurements. Although research laboratories use generally sophisticated analytical methods such as GLC to analyse and quantify lipid samples, chemical derivatie: ations are often used in hospitals. For these methods, the lipid samples are derivatized to yield a product which can be measured simply and accurately-usually by colour. Thus, total triacylglycerol, cholesterol or phospholipid-phosphorus can be quantitated conveniently without bothering with the extra information of molecular species, etc. which might be determined by more thorough analyses. REFERENCES Christie, w.w. (1982) Lipid Analysis, 2nd edn, Pergamon Press, Oxford."

Biochemistry of Lipids Lipoproteins and Membranes

One area of expanding interest is the production of lipid hormones and signal molecules . Several lipids including ... Application of molecular genetics and genomics to problems in lipid biochemistry should continue to expand .

Author: Dennis E. Vance

Publisher: Elsevier

ISBN: 0444511393

Category: Medical

Page: 607

View: 338

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The first edition of this book was published in 1985. The content of the 4th edition reflects the enormous advances that have occurred since that time in the field of lipid biochemistry. This publication is unique in that it represents a bridge between the superficial coverage of the lipid field found in basic biochemistry text books and the highly specialized material contained in scientific review articles and monographs. The book is not a collection of exhaustive reviews, but a current and readable summary of diverse aspects of lipids. It is intended as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry and will also serve as a general reference book for scientists studying lipids, lipoproteins and membranes.

The Lipid Handbook with CD ROM Third Edition

In Biochemistry of Lipids, Lipoprotein and Membranes, Eds.D.E. Vance and J. Vance, Elsevier, Amsterdam, pp. 171–203. Brindley, D.N. and Sturton, R.G. (1982). Phosphatidate metabolism and its relation to triglycerol biosynthesis.

Author: Frank D. Gunstone

Publisher: CRC Press

ISBN: 1420009672

Category: Science

Page: 1472

View: 501

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Extensively revised, reorganized, and expanded, the third edition of the industry standard, The Lipid Handbook reflects many of the changes in lipid science and technology that have occurred in the last decade. All chapters have been rewritten, many by new authors, to match the updated thinking and practice of modern lipid science and bring a fresh perspective to twenty years of tradition. Retaining the general structure of the previous editions, The Lipid Handbook with CD-ROM, Third Edition collates a wide range of information into a single volume. New contributions highlight the latest technologies utilized in today's lipid science such as chromatographic analysis and nuclear magnetic resonance spectroscopy. An entirely new chapter is devoted to non-food uses such as lipids as surfactants, cosmetics, and biofuels. Expanded sections illustrate a growing emphasis on lipid metabolism and the nutritional, medical, and agricultural aspects including human dietary requirements and disorders of lipid metabolism. The dictionary section is vastly expanded to cover chemical structure, physical properties, and references to thousands of lipid and lipid related molecules. The handbook now includes a CD-ROM that allows instant access to tabulated and referenced information and can be searched either as the full text or by structure or substructure. Drawing from the best minds in the field, The Lipid Handbook with CD-ROM, Third Edition presents the latest technological developments and the current and future directions and applications of lipid science to the next generation of researchers.

Biochemistry of Lipids Lipoproteins and Membranes

The 5th edition of this book has been written with two major objectives. The first objective is to provide students and teachers with an advanced up-to-date textbook covering the major areas of current interest in the lipid field.

Author: J.E. Vance

Publisher: Elsevier

ISBN: 0080559883

Category: Science

Page: 624

View: 173

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Research on the biochemistry and molecular biology of lipids and lipoproteins has experienced remarkable growth in the past 20 years, particularly with the realization that many different classes of lipids play fundamental roles in diseases such as heart disease, obesity, diabetes, cancer and neurodegenerative disorders. The 5th edition of this book has been written with two major objectives. The first objective is to provide students and teachers with an advanced up-to-date textbook covering the major areas of current interest in the lipid field. The chapters are written for students and researchers familiar with the general concepts of lipid metabolism but who wish to expand their knowledge in this area. The second objective is to provide a text for scientists who are about to enter the field of lipids, lipoproteins and membranes and who wish to learn more about this area of research. All of the chapters have been extensively updated since the 4th edition appeared in 2002. Key Features: * Represents a bridge between the superficial coverage of the lipid field found in basic biochemistry text books and the highly specialized material contained in scientific review articles and monographs. * Allows scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances. * Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry.

Plant Lipid Biochemistry Structure and Utilization

the proceedings of the Ninth International Symposium on Plant Lipids, held at Wye College, Kent, July 1990 Peter J. Quinn, John L. Harwood. nt Lipid chemistry, cture and ilization Edited by N andJ.L HARWOOD Plant Lipid Biochemistry, ...

Author: Peter J. Quinn

Publisher:

ISBN: UCAL:B4456805

Category: Plant anatomy

Page: 483

View: 938

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The 9th International Symposium on Plant Lipid Biochemistry was held at Wye College, Kent, in July 1990. Not only has the scale and scope of the topic expanded since the first biannual meeting in 1974, but there have been giant strides, particularly in the last few years, in our knowledge of the detailed structure and function of plant lipids. Industry has never been slow to recognize the commercial importance of plant lipids and has invested heavily in the new technologies described in this book. Virtually all the laboratories that have contributed to these developments were represented at the meeting, and this volume is a compendium of their individual contributions.

Lipid Biochemistry An Introduction

In the preface to the Second edition, we made a prediction that many exciting developments would take place in the coming years that would change the face of a new edition.

Author: M. I. Gurr

Publisher: Springer

ISBN: 9400959095

Category: Science

Page: 248

View: 405

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In the preface to the Second edition, we made a prediction that many exciting developments would take place in the coming years that would change the face of a new edition. This has indeed been the case and the current edition reflects these new advances. Our picture of the structure of the fatty acid synthetase has changed dramatically, bringing a new concept in enzymology - the multicatalytic polypeptide chain. This new knowledge owes much to the exploitation of genetic mutants, the use of which is undoubtedly going to extend into many other areas of lipid biochemistry. An understanding of the control of lipid metabolism has also advanced considerably during the last decade and we have tried to reflect that here, although it will be some years before a truly integrated picture can be obtained. For this reason we have continued to deal with the control of particular aspects of lipid metabolism - fatty acids, triacylglycerols, lipoprotein- in the specific chapters but we can foresee the time when a chapter on the overall integration of lipid metabolism will be appropriate and feasible. As a particular example, the exciting new concepts of the control of cholesterol metabolism in specific tissues via the interaction of low density lipoproteins with cell surface receptors have been described in Chapter 6.

Lipid Biochemistry

Lipids can usually be extracted easily from tissues by making use of their hydrophobic characteristics.

Author: J.L. Harwood

Publisher: Springer Science & Business Media

ISBN: 9781461538622

Category: Science

Page: 406

View: 130

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Lipids can usually be extracted easily from tissues by making use of their hydrophobic characteristics. However, such extractions yield a complex mixture of different lipid classes which have to be purified further for quantitative analysis. Moreover, the crude lipid extract will be contami nated by other hydrophobic molecules, e.g. by intrinsic membrane proteins. Of the various types of separation processes, thin layer and column chromatography are most useful for intact lipids. High performance liquid chromatography (HPLC) is also rapidly becoming more popular, especially for the fractionation of molecular species of a given lipid class. The most powerful tool for quantitation of the majority of lipids is gas liquid chromatography (GLC). The method is very sensitive and, if adapted with capillary columns, can provide information with regard to such subtle features as the position or configuration of substitutions along acyl chains. By coupling GLC or HPLC to a radioactivity detector, then the techniques are also very useful for metabolic measurements. Although research laboratories use generally sophisticated analytical methods such as GLC to analyse and quantify lipid samples, chemical derivatie:ations are often used in hospitals. For these methods, the lipid samples are derivatized to yield a product which can be measured simply and accurately-usually by colour. Thus, total triacylglycerol, cholesterol or phospholipid-phosphorus can be quantitated conveniently without bothering with the extra information of molecular species, etc. which might be determined by more thorough analyses. REFERENCES Christie, w.w. (1982) Lipid Analysis, 2nd edn, Pergamon Press, Oxford.